The R&D organisation drives therapeutic innovation from the lab bench to the patient bedside. It develops DNDi’s portfolio of drug candidates from the onset (with the design of target product profiles) to the end point (enabling patients’ access to the new treatments). With members located in various DNDi offices worldwide, R&D teams are key enablers of DNDi’s virtual research model which relies on collaborative partnerships with industry and science partners worldwide, fully inclusive of LMICs clinicians and researchers. Projects are run by project leaders and team members regrouping needed expertise from all DNDi functions, beyond R&D.
The R&D organisation include three clusters of Diseases expert teams: NTD/Mycetoma and Leishmaniasis, NTD/Chagas-Filarial-HAT and Viral Diseases. Integrated Clinical Development Sciences (Drug Safety & Pharmacovigilance, Clinical Quality Assurance and Translational Sciences), Regulatory Sciences, Global Clinical Operations, R&D Portfolio and Planning, Discovery and Pharmaceutical Development teams complement the R&D expertise. Projects review, science and strategy is managed by the Scientific Internal Review Committee (SIRC); The R&D Coordination team lead the R&D organisation for all other topics.
Counting the Kenya Medical Research Institute as a founding partner and numerous collaborations with science and access leaders in the broader East African region, DNDi established itself in 2003 in Nairobi. An integral part of DNDi’s global network, DNDi Eastern Africa nurtures R&D and access partnerships across East Africa and beyond, while contributing to DNDi's global strategy. It hosts key global functions such as global clinical operations, communications, policy advocacy and operations. It leads regional networks and initiatives in R&D and access such as the Leishmaniasis East Africa Platform, and is also home to DNDi’s Data Centre, processing and leading the statistical analysis of clinical trials data for DNDi and a growing cadre of African global health and science groups.
The Senior Clinical Research Associate is responsible for the set-up and follow-up of a range of clinical trials / observational studies in sites according to DNDi’s SOPs, applicable regulation and Good Clinical Practice, other ICH Guidelines and in compliance with overall local, regional and international regulatory obligations associated with the study/ies conducted. Where applicable, to ensure the safety of the patients participating in clinical trials and get reliable clinical data. (Clinical trial set-up and clinical trial monitoring). The incumbent acts as lead CRA, managing a team of CRAs who are monitoring the studies.
DNDi is committed to building a diverse, equitable and truly inclusive organisation. Our success and global reach are dependent upon our ability to encourage diversity and draw on the skills, understanding and experience of all our people. We particularly welcome applications from those who are underrepresented in at DNDi and across the sector, especially women, and including, but not limited to, black and minority ethnic candidates, and those with other protected characteristic.