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The Drugs for Neglected Diseases initiative (DNDi) is an international, not-for-profit research and development (R&D) organization that develops and delivers new treatments for neglected diseases affecting millions of the world’s poorest people.
Together with more than 200 public research and industry allies worldwide, we use the power of partnership, innovation, open science, and advocacy to find solutions to a great injustice: the lack of medicines for life-threatening diseases that disproportionately impact poor and marginalized people. Driven by collaboration, not competition, and by patients’ needs, not profits, we promote equitable access, foster inclusive and sustainable solutions, and advocate for a more effective global biomedical R&D system that meets the needs of neglected patients.
13 new treatments for people with sleeping sickness, visceral leishmaniasis, Chagas disease, HIV, hepatitis C, and malaria that have saved millions of lives. We aim to deliver a total of 25 new treatments by 2028– addressing R&D gaps for neglected tropical diseases and viral infections, including new pandemic-prone diseases (such as COVID-19) and climate-sensitive diseases (such as dengue) with a focus on the needs of patients in low- and middle-income countries.
With more than 240 employees of 30+ nationalities located in nine offices on four continents, DNDi is committed to diversity, equity, and inclusion as essential parts of our culture and key drivers of our success. We encourage candidates of diverse profiles and backgrounds to apply.
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The Senior Clinical Research Associate is responsible for the set-up and follow-up of a range of clinical trials / observational studies in sites according to DNDi’s SOPs, applicable regulation and Good Clinical Practice, other ICH Guidelines and in compliance with overall local, regional and international regulatory obligations associated with the study/ies conducted. Where applicable, to ensure the safety of the patients participating in clinical trials and get reliable clinical data. (Clinical trial set-up and clinical trial monitoring). The incumbent acts as lead CRA, managing a team of CRAs who are monitoring the studies.
Overall Purpose:
The Pharmaceutical Development Officer coordinates Chemistry, Manufacturing and Control (CMC) activities. This role also provides support to the whole Pharmaceutical Development team. This role will contribute to the development and management of pharmaceutical quality systems to assure compliance with GMP and GDP requirements.
Contribution
This role provides specialist services to operational line or project team, working within tried and tested policy, process or practice. This role solves non-routine problems on a case by case/project basis, in consultation with other colleagues or supervisors.
The Discovery Data Scientist will assist the discovery team to deliver on the team objectives and plays a critical role for the
progression of DNDi Hit generation and Lead Optimization (LO) projects up to preclinical candidate delivery.
Key focus of the role:
· Responsible to ensure that the DNDi discovery compound & data management system is adequate and meets the need
of the discovery department of the organization.
· Ensure the integration of novel R&D tools into current workflows to increase the efficiency and ability to incorporate
emerging technologies e.g. AI , Machine learning in the organization. The role may also include direct or indirect support
to the DNDi disease teams .
·...
